Europass Curriculum Vitae Personal information First name(s) / Surname(s) Address(es) Carolina Scagnolari Department of Molecular Medicine, Laboratory of Virology Porta Tiburtina 28, 00185 Rome Telephone(s) +39 0644741246 Fax(es) +39 0644741236 E-mail Nationality Date of birth Gender Mobile: NA [email protected] Italian 01.21.1975 Female Occupational field Virology Work experience • • • • • • • • Occupation or position held Main activities and responsibilities 2001-2004: PhD student in Experimental Medicine (Sapienza University of Rome, Italy) 2001: Visiting research scientist Retrovirus Centre and Virology Section, Department of Experimental Pathology, University of Pisa, Pisa, Italy 2003: Visiting research scientist Viral Pathogens and Biosafety Unit, Vita-Salute San Raffaele University, School of Medicine, Milan, Italy 2005 and 2010: Postdoctoral Fellows (sponsored by ANLAIDS ONLUS -Associazione Nazionale per la Lotta contro l'AIDS). 2005: Visiting research scientist Joan and Sanford I. Weill Medical College, Cornell University, New York City, USA 2007: Postdoctoral Fellows (sponsored by Policlinico Universitario Agostino Gemelli-Università Cattolica del Sacro Cuore, Rome, Italy) 2009: Postdoctoral Fellows (sponsored by Sapienza University of Rome, Italy) 2010: Assistant professor of Virology at Sapienza University of Rome, Italy Assistant Professor Responsible for under/postgraduate teaching/supervision and research in medical virology Research Interests: role of interferon in acute and chronic viral infections; interferon and their therapeutic applications; detection, pathogenesis, and therapy of respiratory viruses Page 1/4 - Curriculum vitae of Surname(s) First name(s) For more information on Europass go to http://europass.cedefop.europa.eu © European Union, 2004-2010 24082010 Name and address of employer Sector Sapienza University of Rome Medical microbiology Education and training 2008: Postgraduate MD specialization course in Microbiology and Virology at the Sapienza University of Rome, Italy 2006: PhD in Experimental Medicine at the Sapienza University of Rome, Italy 2000: Degree in Biological Sciences at the Sapienza University of Rome, Italy (degree 110/110 with honours). Personal skills and competences Molecular and cellular biology techniques Mother tongue(s) Italian Other language(s) Self-assessment European level (*) English Spanish Understanding Speaking Spoken interaction Writing Listening Reading Spoken production B2 B2 B2 B2 B2 A1 A1 A1 A1 A1 (*) Common European Framework of Reference for Languages Additional information Reviewer for the following journals: Journal of interferon and citokines research; Journal of BMC infectious diseases; Journal of Clinical Microbiology and Infection; New Microbiologica; Archives of Virology. Page 2/4 - Curriculum vitae of Surname(s) First name(s) For more information on Europass go to http://europass.cedefop.europa.eu © European Union, 2004-2010 24082010 Scientific Publication 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. Page 3/4 - Curriculum vitae of Surname(s) First name(s) Midulla F, Pierangeli A, Cangiano G, Bonci E, Salvadei S, Scagnolari C, Moretti C, Antonelli G, Ferro V, Papoff P. Rhinovirus bronchiolitis and recurrent wheezing: one year follow-up. Eur Respir J. 2011. IF 5.922 Scagnolari C, Trombetti S, Selvaggi C, Carbone T, Monteleone K, Spano L, Di Marco P, Pierangeli A, Maggi F, Riva E, Antonelli G. In vitro sensitivity of human metapneumovirus to type I interferons. Viral Immunol. 2011; 24(2):159-64. IF 1.871 Scagnolari C, Trombetti S, Soldà A, Selvaggi C, Monteleone K, Spano L, Pierangeli A, Clementi M, Turriziani O, Antonelli G. Pandemic 2009 H1N1 influenza virus is resistant to the antiviral activity of several interferon alpha subtypes. J Interferon Cytokine Res. 2011; 31(6):475-9. IF 2.576 Scagnolari C, Zingariello P, Vecchiet J, Selvaggi C, Racciatti D, Taliani G, Riva E, Pizzigallo E, Antonelli G. Differential expression of interferon-induced microRNAs in patients with chronic hepatitis C virus infection treated with pegylated interferon alpha. Virol J. 2010; 7:311. IF 2.55 Pierangeli A, Scagnolari C, Gentile M, Spina MT, Iudicello A, Bertazzoni G, Antonelli G. Virological diagnosis of respiratory virus infection in patients attending an emergency department during the influenza season. Clin Microbiol Infect. 2010; 16(4):391-3. IF 4.784 Midulla F, Scagnolari C, Bonci E, Pierangeli A, Antonelli G, De Angelis D, Berardi R, Moretti C. Respiratory syncytial virus, human bocavirus and rhinovirus bronchiolitis in infants. Arch Dis Child. 2010; 95(1):35-41. IF 2.616 Pierangeli A, Scagnolari C, Trombetti S, Grossi R, Battaglia M, Moretti C, Midulla F, Antonelli G. Human bocavirus infection in hospitalized children in Italy. Influenza Other Respi Viruses. 2008; 2(5):175-9. IF 3.812 Scagnolari C, Selvaggi C, Chiavuzzo L, Carbone T, Zaffiri L, d'Ettorre G, Girardi E, Turriziani O, Vullo V, Antonelli G. Expression levels of TLRs involved in viral recognition in PBMCs from HIV-1infected patients failing antiretroviral therapy. Intervirology. 2009; 52(2):107-14. IF 1.756 Scagnolari C, Midulla F, Pierangeli A, Moretti C, Bonci E, Berardi R, De Angelis D, Selvaggi C, Di Marco P, Girardi E, Antonelli G. Gene expression of nucleic acid-sensing pattern recognition receptors in children hospitalized for respiratory syncytial virus-associated acute bronchiolitis. Clin Vaccine Immunol. 2009; 16(6):816-23 IF 2.471 Pierangeli A, Scagnolari C, Degener AM, Bucci M, Ciardi A, Riva E, Indinnimeo M, Mancini G, D'Ettorre G, Vullo V, Antonelli G. Type-specific human papillomavirus-DNA load in anal infection in HIV-positive men. AIDS. 2008; 22(15):1929-35 IF 6.348 Riva E, Maggi F, Abbruzzese F, Bellomi F, Giannelli G, Picardi A, Scagnolari C, Folgori A, Spada E, Piccolella E, Dianzani F, Antonelli G; Acute Hepatitis C Italian Study Group. Immune complexed (IC) hepatitis C virus (HCV) in chronically and acutely HCV-infected patients. Med Microbiol Immunol. 2009; 198(1):13-8. IF 3.27 Scagnolari C, Midulla F, Trombetti S, Pierangeli A, Tromba V, Grossi R, Di Marco P, Dianzani C, Girardi E, Antonelli G. Upregulation of interferon-induced genes in infants with virus-associated acute bronchiolitis. Exp Biol Med 2007; 232(10):1355-9. IF 2.954 Bruno R, Sacchi P, Scagnolari C, Torriani F, Maiocchi L, Patruno S, Bellomi F, Filice G, Antonelli G. Pharmacodynamics of peginterferon alpha-2a and peginterferon alpha-2b in interferon-naïve patients with chronic hepatitis C: a randomized, controlled study. Aliment Pharmacol Ther. 2007; 26(3):369-76. IF 3.861 Scagnolari C, Duda P, Bagnato F, De Vito G, Alberelli A, Lavolpe V, Girardi E, Durastanti V, Trojano M, Kappos L, Antonelli G. Pharmacodynamics of interferon beta in multiple sclerosis patients with or without serum neutralizing antibodies. J Neurol. 2007; 254(5):597-604 IF 3.853 Pierangeli A, Gentile M, Di Marco P, Pagnotti P, Scagnolari C, Trombetti S, Lo Russo L, Tromba V, Moretti C, Midulla F, Antonelli G. Detection and typing by molecular techniques of respiratory viruses in children hospitalized for acute respiratory infection in Rome, Italy. J Med Virol. 2007; 79(4):463-8 IF 2.895 For more information on Europass go to http://europass.cedefop.europa.eu © European Union, 2004-2010 24082010 16. Turriziani O, Bucci M, Stano A, Scagnolari C, Bellomi F, Fimiani C, Mezzaroma I, D'Ettorre G, Brogi A, Vullo V, Antonelli G. Genotypic resistance of archived and circulating viral strains in the blood of treated HIV-infected individuals. JAcquir Immune Defic Syndr. 2007; 44(5):518-24 IF 4.262 17. Scagnolari C, Bellomi F, Trombetti S, Casato M, Carlesimo M, Bagnato F, Lavolpe V, Bruno R, Millefiorini E, Antonelli L, Girardi E, Turriziani O, Antonelli G. Expression of biomarkers of interferon type I in patients suffering from chronic diseases. Clin Exp Immunol. 2007; 147(2):270-6 IF 3.009 18. Riva E, Serraino D, Pierangeli A, Bambacioni F, Zaniratti S, Minosse C, Selleri M, Bucci M, Scagnolari C, Degener AM, Capobianchi MR, Antonelli G, Dianzani F; Roman Papillomavirus Study Group*. Markers of human papillomavirus infection and their correlation with cervical dysplasia in human immunodeficiency virus-positive women. Clin Microbiol Infect. 2007; 147(2):270-6 IF 4.784 19. Santantonio T, Milella M, Antonelli G, Scagnolari C. Neutralizing antibodies to interferon alpha in a chronic hepatitis C patient non-responder to pegylated interferon. J Hepatol. 2006; 45(5):759-61. IF 9.334 20. Scagnolari C, Vicenzi E, Bellomi F, Stillitano MG, Pinna D, Poli G, Clementi M, Dianzani F, Antonelli G. Increased sensitivity of SARS-coronavirus to a combination of human type I and type II interferons. Antivir Ther. 2004; 9(6):1003-11 IF 3.77 21. Casato M, Lilli D, Donato G, Granata M, Conti V, Del Giudice G, Rivanera D, Scagnolari C, Antonelli G, Fiorilli M. Occult hepatitis C virus infection in type II mixed cryoglobulinaemia. J Viral Hepat. 2003; 10(6):455-9 IF 3.502 22. Bellomi F, Scagnolari C, Tomassini V, Gasperini C, Paolillo A, Pozzilli C, Antonelli G. Fate of neutralizing and binding antibodies to IFN beta in MS patients treated with IFN beta for 6 years. J Neurol Sci. 2003; 15;215(1-2):3-8 IF 2.167 23. Antonelli G, Scagnolari C, Vicenzi E, Clementi M. Treatment of SARS with human interferons. Lancet. 2003; 362(9390):1158 IF 33.633 24. Riva E, Antonelli G, Scagnolari C, Pistello M, Capobianchi MR, Monforte A, Pezzotti P, Dianzani F; I.CO.N.A. Study Group. Human immunodeficiency virus (HIV) DNA load and level of immunosuppression in treatment-naive HIV-1-infected patients. J Infect Dis. 2003; 187(11):1826-8 IF 6.288 25. Scagnolari C, Casato M, Bellomi F, De Pisa F, Turriziani O, Coviello R, Pirro MR, Dianzani F, Antonelli G. Serum interferon (IFN)-neutralizing antibodies and bioactivities of IFNs in patients with severe type II essential mixed cryoglobulinemia. Clin Diagn Lab Immunol. 2003; 10(1):70-7 IF 2.51 26. Turriziani O, Scagnolari C, Bambacioni F, Bellomi F, Focher F, Gentile M, Antonelli G. Selection of a T-cell line resistant to stavudine and zidovudine by prolonged treatment with stavudine. Antivir Ther. 2002; 7(2):105-11 IF 3.77 27. Giannelli G, De Marzo A, Scagnolari C, Bergamini C, Fransvea E, Bagnato F, Bellomi F, Millefiorini E, Gasperini C, Antonaci S, Antonelli G. Proteolytic balance in patients with multiple sclerosis during interferon treatment. JInterferon Cytokine Res. 2002; 22(6):689-92 IF 2.576 28. Bagnato F, Pozzilli C, Scagnolari C, Bellomi F, Pasqualetti P, Gasperini C, Millefiorini E, Galgani S, Spadaro M, Antonelli G. A one-year study on the pharmacodynamic profile of interferon-beta1a in MS. Neurology. 2002; 58(9):1409-11 IF 8.17 29. Scagnolari C, Bellomi F, Turriziani O, Bagnato F, Tomassini V, Lavolpe V, Ruggieri M, Bruschi F, Meucci G, Dicuonzo G, Antonelli G. Neutralizing and binding antibodies to IFN-beta: relative frequency in relapsing-remitting multiple sclerosis patients treated with different IFN-beta preparations. J Interferon Cytokine Res. 2002; 22(2):207-13 IF 2.576 Textbooks (Chapters, etc.) Page 4/4 - Curriculum vitae of Surname(s) First name(s) 1.Scagnolari C, Bellomi F, Antonelli L, Iaiani G, Turriziani O, Roffi L, Radaelli A, Dianzani F, Antonelli G. Misurazione dell’espressione della proteina MxA come marcatore di risposta alla terapia con Interferon alfa in pazienti affetti da epatite cronica C. L’Igiene Moderna, Vol CXXI N.2, pp 67-81, 2004. 2.Scagnolari C, Antonelli G, Pierangeli A, Riva E, Dianzani F. Expression of Interferon-induced Markers in Patients with Different Chronic Diseases. Interferon: Current Status 2007. Editore Kailash C. Chadha Research Signpost, T. C. 37/661(2). 3.Antonelli G, Bellomi F, Turriziani O, Bagnato F, Scagnolari C, Dianzani F. In Vivo Development of Antibody to IFNs in IFN-Treated Patients: Considerations after 25 years From the Discovery Interferon: Curren Status, 2007. Editore Kailash C. Chadha. Research Signpost, T. C. 37/661(2). 4.Antonelli G, Scagnolari C. Sistema Interferon, Principi di Virologia Medica 2007, capitolo 62, b353-b360. Editore Ambrosiana, Italia. For more information on Europass go to http://europass.cedefop.europa.eu © European Union, 2004-2010 24082010