Pisa University Hospital
University of Pisa
Regione Toscana
VIRUSES AND BREAST CANCER
INTERNATIONAL WORKSHOP
April 2 - 4, 2012
Palazzo Blu
LUNGARNO GAMBACORTI, 9
PISA
THE WORKSHOP
IS IN THE FRAME OF THE REGIONE TOSCANA RESEARCH PROJECT “IS BREAST
CANCER CAUSED BY A VIRUS? STUDY ON THE ETIOLOGICAL ROLE, PATHOGENETIC MECHANISMS AND
SPREADING OF THE HUMAN MAMMARY TUMOR VIRUS INFECTION”
UNDER THE AUSPICES OF THE EUROPEAN SOCIETY OF PATHOLOGY
AND OF ISTITUTO TOSCANO TUMORI
IN COLLABORATION WITH
THE “PALAZZO BLU” FOUNDATION
APRIL 2, MONDAY
14:00 Welcome Addresses
14:30 Generoso Bevilacqua
Remembering Francesco Squartini, 1927-1992.
Session I
CHAIR: JAMES LAWSON, HARALD ZUR HAUSEN 14:45 Harald zur Hausen
Viruses in human cancers: reasons to suspect an involvement of infections in human breast
cancer?
15:30 Gertrude Buehring
Could Bovine Leukemia Virus play a role in human breast cancer?
16:15 Discussion
16:30 COFFEE
Session II
CHAIR: GERTRUDE BUEHRING, EZEQUIEL MOISES FUENTES PANANÁ 17:00 Mauro Pistello
The expanding world of polyomaviruses and cancer.
17:30 James Lawson
Multiple viruses in breast cancer: Mouse Mammary Tumor Virus (MMTV), Epstein Barr
Virus (EBV), Human Papilloma Virus (HPV), Bovine Leukemia Virus (BLV).
18:15 Discussion
APRIL 3, TUESDAY
Session III
CHAIR: JACOB HOCHMAN, SUSAN ROSS 9:00
Beatriz Pogo
MMTV in human cancer, an overview
9:45
Brian Salmons, Walter Gunzburg
Past and future perspectives on MMTV
10:30 Discussion
10:45 COFFEE
Session IV
CHAIR: BEATRIZ POGO, ALEXANDER STEWART 11:15 Generoso Bevilacqua, Chiara Maria Mazzanti
MMTV in sporadic and hereditary human breast cancer.
12:00 Jaquelin Dudley
What factors affect MMTV replication in human cells?
12:45 Discussion
13:00 LUNCH
Session V
CHAIR: JAQUELIN DUDLEY, CHIARA MARIA MAZZANTI 14:30 Robert Callahan
Common integration sites for MMTV in mammary tumors and their involvement in
tumorigenesis.
15:15 Susan Ross
MMTV integration site analysis uncovers new pathways involved in breast cancer.
16:00 Discussion
16:15 COFFEE
Session VI
CHAIR: STELLA MELANA, BRIAN SALMONS 16:45 Andrew Mason
Providing definitive proof of MMTV-like viruses in humans: isolation of the human
betaretrovirus and detection of integration sites in patients.
17:30 Jacob Hochman
New insights into tumor growth regulation by the signal peptide of MMTV-env.
18:15 Discussion
APRIL 4, WEDNESDAY
Session VII
CHAIR: WALTER GUNZBURG , ANDREW MASON 9:00
Stella Melana
The host response to HMTV infection
9:45
Ezequiel Moises Fuentes Pananá
Screening of EBV, MMTV and HHV7 sequences in breast cancer samples from Mexico.
10:30 Discussion
10:45 COFFEE
Session VIII
CHAIR: ROBERT CALLAHAN, MAURO PISTELLO 11:15 Alexander Stewart
Breast cancer incidence spikes and mouse population explosions in New South Wales,
Australia.
11:45 General Discussion
12:15 Generoso Bevilacqua
General comment and future plans
Speakers:
•
Generoso Bevilacqua, University of Pisa and Pisa University Hospital, Italy
•
Gertrude Buehring, University of California, Berkeley, CA, USA
•
Robert Callahan, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD,
USA
•
Jaquelin Dudley, University of Texas, Austin, TX, USA
•
Ezequiel Moises Fuentes Pananá, Hospital de Pediatría, Mexico City, Mexico
•
Walter Gunzburg, University of Veterinary Medicine, Vienna, Austria
•
Jacob Hochman, The Hebrew University, Jerusalem, Israel
•
James Lawson, University of New South Wales, Sydney, Australia
•
Andrew Mason, University of Alberta, Canada
•
Chiara Maria Mazzanti, University of Pisa and Pisa University Hospital
•
Stella Melana, Mount Sinai School of Medicine, New York, NY, USA
•
Mauro Pistello, University of Pisa and Pisa University Hospital, Italy
•
Beatriz Pogo, Mount Sinai School of Medicine, New York, NY, USA
•
Susan Ross, University of Pennsylvania, Philadelphia, PA, USA
•
Brian Salmons, Austrianova Singapore Pte Ltd, Singapore
•
Alexander Stewart, University of Ottawa, Ottawa, Canada
•
Harald zur Hausen, German Cancer Research Center, Heidelberg, Germany
“Palazzo Blu” - Lungarno Gambacorti, 9 - Pisa
Leaning Tower
Grand’Hotel Duomo
University of Pisa
Palazzo Blu
